What Is Ozone Therapy and What Are Its Benefits? The Longevity Approach

The Biological Mechanism of Action of Ozone Gas in the Body

Ozone therapy is the process of administering medical ozone gas (an unstable molecule consisting of three oxygen atoms) to the body in a controlled manner. As soon as ozone gas comes into contact with the blood, it rapidly reacts, triggering beneficial biochemical processes in the body:

1. Increased Oxygen Carrying Capacity: Ozone increases the flexibility of red blood cells (erythrocytes), allowing them to pass through capillaries more easily. It also maximizes oxygenation at the cellular level by enhancing the cells’ ability to release oxygen to the tissues.
2. Activation of Antioxidant Systems: It combats free radicals and cellular aging by activating antioxidant enzymes (glutathione peroxidase, superoxide dismutase), which are the body’s own defense mechanisms.
3. Regulation of the Immune System (Immunomodulation): At low doses, ozone stimulates the immune system, thereby increasing resistance to infections, while also helping to balance overactive immune responses (autoimmune diseases).

Medical Ozone Therapy Methods

At our outpatient clinic, ozone therapy treatments are administered using various methods tailored to the patient's needs:

• Major Ozone Therapy: This is the most common method. 50–100 ml of blood drawn from the patient is mixed with medical-grade ozone gas in a sterile system and then reinfused into the body.
• Minor Ozone Therapy: It involves taking a small amount of blood from the patient, ozonating it, and reinjecting it into the muscle; it is typically administered to boost the immune system and reduce allergies.
• Ozone Sauna: This is a cabin treatment designed for detoxification and skin rejuvenation that facilitates the absorption of ozone in vapor form through the skin’s pores.

Who Should Not Undergo Ozone Therapy? (Contraindications)

Although ozone therapy is a natural, safe, and virtually side-effect-free complementary treatment method, its use is strictly contraindicated in certain specific health conditions. These conditions are referred to as “contraindications” in the medical literature:

1. Favism (Glucose-6-Phosphate Dehydrogenase Deficiency): Ozone therapy must never be administered to individuals with this hereditary enzyme deficiency—commonly known as fava bean allergy—as it can cause the breakdown of red blood cells (hemolysis).
2. Hyperthyroidism (Toxic Goiter): In patients with an overactive thyroid gland and uncontrolled hormone levels, ozone gas poses a risk because it can further accelerate metabolism.
3. Severe Anemia and Bleeding Disorders: Ozone therapy, which increases blood fluidity, cannot be administered to patients with a clotting disorder such as hemophilia or those with active internal bleeding.
4. The First Three Months of Pregnancy: Ozone therapy is not recommended during the first trimester of pregnancy (the first 3 months) because the baby’s organ development is still ongoing.
5. Recent Heart Attack and Stroke: Immediately following a cardiovascular event during the acute phase (the first month), the body is expected to stabilize.

Precautions to Take Before and After Ozone Therapy Sessions

To get the most out of ozone therapy sessions and prevent any possible mild side effects, there are some important points our patients should keep in mind:

• Coming on a Full Stomach: You should definitely not come to ozone therapy sessions on an empty stomach. Eating a light meal before the session helps maintain stable blood sugar levels.
• Plenty of Water Consumption: Ozone gas accelerates the body’s detoxification mechanisms. To ensure that the toxins released during this process can be easily eliminated from the body through the kidneys, you should drink at least 2–2.5 liters of water on the day of your session.
• Alcohol and Medication Use: Alcohol consumption must be stopped at least 24 hours before the sessions. In addition, if you are taking any regular medications, you must inform our specialist in advance.
• Vitamin C Supplements: Since high doses of vitamin C may neutralize the antioxidant effect of ozone gas, vitamin C supplements should not be taken on treatment days.

Safety Standards and Quality Control in Medical Ozone Therapy

Medikal ozon terapi uygulamasında kullanılan cihazların ve sarf malzemelerinin kalitesi, işlemin güvenliği açısından birinci derecede önemlidir. Ozon gazı yüksek oksidatif güce sahip olduğu için, sıradan plastik veya metallerle temas ettiğinde bu malzemeleri eritebilir ve toksik maddelerin açığa çıkmasına neden olabilir. Bu nedenle Medlook Polikliniği’nde kullanılan tüm ekipmanlar, ozona %100 dayanıklı olan özel cam, teflon ve silikon malzemelerden üretilmiştir. Majör ozon terapi işleminde kullanılan kan torbaları ve hortum setleri tek kullanımlık ve sterildir. Ozon jeneratörlerimiz ise anlık olarak verilen gazın konsantrasyonunu ölçen hassas fotometrik ölçüm sistemlerine sahiptir. Bu sayede hastalarımıza her seansta tam olarak doktorumuzun reçete ettiği güvenli dozda ozon uygulaması yapılmaktadır.

At Medlook Clinic in Nişantaşı, our medical ozone therapy treatments are administered according to the safest clinical protocols after our specialist physician has assessed the patient’s overall health. You can contact our clinic to protect your health and regenerate your cells. The success of ozone therapy depends on the session frequency and dosage adjustments determined specifically for each individual. For this reason, a pre-treatment consultation with a doctor is of vital importance.