Can smart filling be dissolved?

No, PCL fillings do not have a dissolving enzyme. Therefore, there is no luxury to say "I don't like it, let's dissolve it". This makes the experience of the practitioner the most critical factor.

Will I feel stiffness in my face?

In the first weeks, a slight hardness may be felt as collagen production begins, this is natural. Over time, it integrates with the tissue and softens completely and gives a natural feeling.

How many sessions do you need?

One session is usually enough. If there are missing areas, a small touch-up can be done after 3 months.

4 Will my face suddenly fade after 4 years?

No, it doesn't. Even if the PCL microspheres dissolve, the collagen tissue it produces is your own tissue and slowly decreases with your aging process. So even when the filler melts, your skin will be in much better condition than before the procedure.

PCL Filling - Private Medlook Polyclinic 2026

PCL (Polycaprolactone):
“Smart Filling” of the Aesthetic World”

Among the technologies revolutionizing aesthetic medicine, one of the concepts that attracts the most attention of our patients is undoubtedly “Smart Filling”is Scientific name PCL (Polycaprolactone), has been developed for those who are tired of the temporary solutions offered by classical fillers and want a longer lasting, more natural and biological repair on their face.Dr. Handan Yavuz There are two main reasons why this special technology that we apply at Medlook Polyclinic is called “Smart”: The first is that it programs your cells like a computer code to produce the Type-1 Collagen your skin needs; the second is that the duration of permanence (from 1 year to 4 years) can be adjusted according to your preference. PCL, which not only fills your face, but also gives your skin a “satin” smooth texture, is one of the most advanced members of the biostimulants class.

What is PCL (Polycaprolactone)? Is it Safe?

Polycaprolactone (PCL) is a biodegradable medical polymer that has been used safely in medicine for over 60 years in dissolving surgical sutures, orthopedic implants and drug delivery systems. It is never permanent in the body; when it expires, it is completely converted into carbon dioxide and water and excreted from the body.

What's Inside the Smart Filler?

PCL Biyostimülanlar, %100 biyolojik olarak parçalanabilir iki ana bileşenden oluşur:

%70 CMC (Karboksimetil Selüloz) Jel Taşıyıcı: This gel provides instant volume and fullness as soon as it is applied. So you don't have to wait to see the result like PLLA (Liquid Thread). The moment you leave the clinic, your wrinkles are filled and your face is lifted.
%30 PCL (Polikaprolakton) Mikro-Küreleri: This is where the magic begins. These perfectly smooth micro-balls settle deep into the skin. While the carrier gel dissolves within 2-3 months, the PCL spheres stimulate fibroblasts to produce “your own natural collagen” to replace them.

You Choose the Duration of Permanence: S, M, L, E Options

The biggest difference of PCL fillers from all other fillers in the world is that the retention time can be adjusted according to the polymer chain length. In your consultation with Dr. Handan Yavuz, you will choose one of the following options according to your aging rate and expectations:

S (Short)

About 1 Year provides permanence. Ideal for first-timers.

M (Medium)

About 2 Years provides permanence. It is the most preferred form.

L (Long)

About 3 Years provides permanence. Suitable for those with deep volume loss.

E (Ellansé-E)

About 4 Years provides permanence. For those who want long-term investment.

Note: Whichever duration you choose, the collagen quality and safety profile created by the filler is the same. Only the melting time of the microspheres changes.

Why Choose PCL Smart Filler?

Compared to classic hyaluronic acid fillers, PCL technology belongs to the “Premium” segment and offers the following advantages

1. “Instant Results + Long Term Investment”

With PLLA (Sculptra), you wait for months to see the result. In PCL, on the other hand, you see instant fullness thanks to the CMC gel. Since collagen is activated as the gel dissolves, an “uninterrupted” state of well-being lasts without loss of fullness.

2. Top Quality Collagen (Type-1) Production

PCL is a protein that is abundant in our skin in infancy and is responsible for skin elasticity. Type-1 Collagen production. This not only plumps the skin but also smoothens its texture like velvet (Satin Effect).

3. Fully Bio-Resorbability

PCL leaves no residues, toxins or foreign substances behind as it metabolizes in the body. At the end of the process, it is completely removed from the body as CO2 (excreted in the breath) and H2O (excreted in the urine).

4. High Volumizing Capacity

It has a stronger lifting capacity than other biostimulants. It makes a dramatic difference especially in deep nasolabial grooves, chin tip retardation and cheekbone collapse even in a single session.

Where is PCL (Smart Filler) Applied?

It is applied on the bone or deep dermis areas where we want to strengthen the architectural structure of the face:

- Temporal Region: To fill sunken temples and raise eyebrows.
- Cheekbones To strengthen the “lifting points” that lift the face up.
- Nasolabial and Marionette Lines: To erase deep shadows around the nose and mouth.
- Jawline and Jaw Tip: To create a sharp and clear profile.
- Rhinoplasty (Non-Surgical): To straighten the back of the nose and lift the tip (thanks to its hard structure, it does not spread).
- Hand Rejuvenation To thicken the skin of aged hands and hide veins.

ABSOLUTELY NOT APPLICABLE REGIONS: PCL Smart Filler; lips (mobile and mucosa), under the eyes (thin skin) and between the eyebrows (glabella) not applicable. Hyaluronic acid should be preferred for these areas.

The Battle of Biostimulants: The PCL, PLLA and CaHA Difference

Our comparison table to help you understand which “Smart” technology is right for you:

Feature	PCL (Smart Fill)	PLLA (Liquid Rope)	CaHA (Mineral Vaccine)
Instant Volume	✅ YES (with CMC Gel)	❌ NO (Over time)	✅ YES (with gel)
Persistence	⭐⭐⭐⭐ (1-4 Years)	⭐⭐⭐⭐⭐ (2+ Years)	⭐⭐⭐ (1.5-2 Years)
Collagen Type	Type-1 (Elasticity)	Type-1 (Tightening)	Type-1 and Type-3
Return (Melting)	❌ None (melts over time)	❌ No	❌ No

Note: No biostimulant (PCL, PLLA, CaHA) has an “instant dissolving enzyme” like hyaluronic acid. Therefore, the application should be done in expert hands such as Dr. Handan Yavuz who has a good command of anatomy.

The Medlook Difference: Protocols “Feeding” Smart Filling

We have ordered your skin to “produce collagen” with PCL, but does your body have the energy to fulfill this order? At Medlook, we don't leave PCL alone, we support the body so that the result is perfect.

1. IV (Intravenous) Vitamin Cocktail

Collagen synthesis requires high amounts of vitamin C. In the same session with PCL application Medlook Atom Serum (IV Vitamin C), acts as a biological “starter” to initiate the effect of the filling.

2. Oxygenation with Ozone Therapy

Cells need oxygen to produce collagen. In patients who smoke or have poor circulation, we improve tissue quality by recommending 1-2 sessions of Ozone Therapy before PCL.

Who is Suitable for PCL Smart Fillers?

Those Tired of Frequent Fillers: “I don't want to come every 6 months, let's do it once, let's make it last longer”.
Face Droopers Middle-older age group with deep nasolabial grooves and sagging cheeks.
Those Who Want Satin Skin: Those who want not only fullness, but also improved skin quality and shine.
Surgery Avoiders: Those looking for a strong non-surgical recovery instead of facelift surgery.

Safety Profile and Side Effects

PCL Smart Filler is a safe material with FDA and CE approvals. However, the correct technique is essential to reduce the risk of granuloma (clumping) to zero.

Pay: There may be mild edema for 2-3 days after the procedure. This indicates that the PCL is a strong stimulant.
Massage Unlike PLLA, there is usually no need for the patient to massage at home after a PCL procedure. The shape is given by the doctor and remains so.

PCL Filling