{"id":21170,"date":"2026-01-28T10:00:33","date_gmt":"2026-01-28T07:00:33","guid":{"rendered":"https:\/\/medlook.com.tr\/?p=21170"},"modified":"2026-01-28T13:26:59","modified_gmt":"2026-01-28T10:26:59","slug":"what-distinguishes-harmonycayi-from-other-biostimulant-fillers","status":"publish","type":"post","link":"https:\/\/medlook.com.tr\/en\/harmonycayi-diger-biyostimulan-dolgulardan-ayiran\/","title":{"rendered":"What are the Key Features that Differentiate HArmonyCA from Other Biostimulant Fillers? Hybrid Filler Revolution"},"content":{"rendered":"<div data-elementor-type=\"wp-post\" data-elementor-id=\"21170\" class=\"elementor elementor-21170\" data-elementor-post-type=\"post\">\n\t\t\t\t<div class=\"elementor-element elementor-element-de8a0e3 e-con-full e-flex e-con e-parent\" data-id=\"de8a0e3\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;ekit_has_onepagescroll_dot&quot;:&quot;yes&quot;}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-e17439f elementor-widget elementor-widget-text-editor\" data-id=\"e17439f\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;ekit_we_effect_on&quot;:&quot;none&quot;}\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<h2>What are the Key Features that Differentiate HArmonyCA from Other Biostimulant Fillers? Hybrid Filler Revolution<\/h2><p>The world of medical aesthetics has been developing at a dizzying pace in recent years. Approaches that used to be based only on \u201cfilling\u201d (volumizing) are now evolving into \u201cregeneration\u201d (regeneration). Our patients no longer just want to fill their sunken cheeks; they also want their loose skin to tighten, improve its quality and resist the effects of time at the cellular level. Two different product groups have been used for a long time to meet this demand: Hyaluronic Acid (HA) fillers that provide instant volume and Biostimulants (Smart Fillers) that produce collagen over time. However, patients were often torn between the dilemma of \u201ceither getting immediate results or making a long-term investment\u201d. At this point, Allergan Aesthetics developed a \u201cParadigm Shift\u201d in aesthetic medicine. <strong>HArmonyCa\u2122<\/strong> took the stage.<br \/><img decoding=\"async\" src=\"https:\/\/medlook.com.tr\/wp-content\/uploads\/2026\/01\/1-13.webp\" alt=\"\" title=\"\"><br \/>HArmonyCa is the world's first \u201cDual Action Hybrid Injectable\u201d. The main feature that distinguishes it from others is that it offers two powerful technologies in perfect harmony in the same injector. On the one hand, Hyaluronic Acid, which provides an instant lifting effect, and Calcium Hydroxyapatite (CaHA), which rebuilds the scaffolding of the skin. <a href=\"https:\/\/medlook.com.tr\/en\/contact\/\" target=\"_blank\" rel=\"noopener sponsored\"><strong>Medlook Polyclinic in Nisantasi, Istanbul<\/strong><\/a> As HArmonyCa, we position HArmonyCa as a \u201cGold Standard\u201d solution in our facial rejuvenation protocols, especially for our patients who experience sagging and loss of elasticity on the sides of the face (lateral). In this comprehensive guide, we will examine the molecular structure of HArmonyCa, why it is completely different from other biostimulants (Sculptra, Radiesse, Ellanse, etc.) and the \u201c1+1=3\u201d effect it creates on your skin in the light of scientific data, down to the finest detail.<\/p><div id=\"ez-toc-container\" class=\"ez-toc-v2_0_83 counter-hierarchy ez-toc-counter ez-toc-light-blue ez-toc-container-direction\">\n<div class=\"ez-toc-title-container\">\n<p class=\"ez-toc-title\" style=\"cursor:inherit\">Featured Headlines<\/p>\n<span class=\"ez-toc-title-toggle\"><a href=\"#\" class=\"ez-toc-pull-right ez-toc-btn ez-toc-btn-xs ez-toc-btn-default ez-toc-toggle\" aria-label=\"Toggle Table of Content\"><span class=\"ez-toc-js-icon-con\"><span class=\"\"><span class=\"eztoc-hide\" style=\"display:none;\">Toggle<\/span><span class=\"ez-toc-icon-toggle-span\"><svg style=\"fill: #999;color:#999\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" class=\"list-377408\" width=\"20px\" height=\"20px\" viewbox=\"0 0 24 24\" fill=\"none\"><path d=\"M6 6H4v2h2V6zm14 0H8v2h12V6zM4 11h2v2H4v-2zm16 0H8v2h12v-2zM4 16h2v2H4v-2zm16 0H8v2h12v-2z\" fill=\"currentColor\"><\/path><\/svg><svg style=\"fill: #999;color:#999\" class=\"arrow-unsorted-368013\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"10px\" height=\"10px\" viewbox=\"0 0 24 24\" version=\"1.2\" baseprofile=\"tiny\"><path d=\"M18.2 9.3l-6.2-6.3-6.2 6.3c-.2.2-.3.4-.3.7s.1.5.3.7c.2.2.4.3.7.3h11c.3 0 .5-.1.7-.3.2-.2.3-.5.3-.7s-.1-.5-.3-.7zM5.8 14.7l6.2 6.3 6.2-6.3c.2-.2.3-.5.3-.7s-.1-.5-.3-.7c-.2-.2-.4-.3-.7-.3h-11c-.3 0-.5.1-.7.3-.2.2-.3.5-.3.7s.1.5.3.7z\"\/><\/svg><\/span><\/span><\/span><\/a><\/span><\/div>\n<nav><ul class='ez-toc-list ez-toc-list-level-1' ><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-1\" href=\"https:\/\/medlook.com.tr\/en\/harmonycayi-diger-biyostimulan-dolgulardan-ayiran\/#HArmonyCAyi_Diger_Biyostimulan_Dolgulardan_Ayiran_Temel_Ozellikler_Nelerdir_Hibrit_Dolgu_Devrimi\" >What are the Key Features that Differentiate HArmonyCA from Other Biostimulant Fillers? Hybrid Filler Revolution<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-2\" href=\"https:\/\/medlook.com.tr\/en\/harmonycayi-diger-biyostimulan-dolgulardan-ayiran\/#Bolum_1_Hibrit_Teknoloji_Nedir_11_Nasil_3_Eder\" >Part 1: What is Hybrid Technology? How Does 1+1 Make 3?<\/a><ul class='ez-toc-list-level-3' ><li class='ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-3\" href=\"https:\/\/medlook.com.tr\/en\/harmonycayi-diger-biyostimulan-dolgulardan-ayiran\/#Icerigin_Anatomisi\" >Anatomy of Content<\/a><\/li><\/ul><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-4\" href=\"https:\/\/medlook.com.tr\/en\/harmonycayi-diger-biyostimulan-dolgulardan-ayiran\/#Bolum_2_HArmonyCayi_Digerlerinden_Ayiran_5_Temel_Fark\" >Part 2: 5 Key Differences that Set HArmonyCa Apart<\/a><ul class='ez-toc-list-level-3' ><li class='ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-5\" href=\"https:\/\/medlook.com.tr\/en\/harmonycayi-diger-biyostimulan-dolgulardan-ayiran\/#1_%22Aninda_Sonuc%22_Farki_Instant_Gratification\" >1. The \"Instant Gratification\" Difference<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-6\" href=\"https:\/\/medlook.com.tr\/en\/harmonycayi-diger-biyostimulan-dolgulardan-ayiran\/#2_Kullanima_Hazir_Formulasyon_No_Preparation\" >2. Ready to Use Formulation (No Preparation)<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-7\" href=\"https:\/\/medlook.com.tr\/en\/harmonycayi-diger-biyostimulan-dolgulardan-ayiran\/#3_Masaj_Gerektirmemesi_Post-Op_Konfor\" >3. No Massage Required (Post-Op Comfort)<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-8\" href=\"https:\/\/medlook.com.tr\/en\/harmonycayi-diger-biyostimulan-dolgulardan-ayiran\/#4_Kompozit_Matriks_Yapisi\" >4. Composite Matrix Structure<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-9\" href=\"https:\/\/medlook.com.tr\/en\/harmonycayi-diger-biyostimulan-dolgulardan-ayiran\/#5_Yan_Etki_Profilinin_Dusuklugu\" >5. Low Side Effect Profile<\/a><\/li><\/ul><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-10\" href=\"https:\/\/medlook.com.tr\/en\/harmonycayi-diger-biyostimulan-dolgulardan-ayiran\/#Bolum_3_Etki_Mekanizmasi_Cildin_Altinda_Neler_Oluyor\" >Section 3: Mechanism of Action: What Happens Under the Skin?<\/a><ul class='ez-toc-list-level-3' ><li class='ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-11\" href=\"https:\/\/medlook.com.tr\/en\/harmonycayi-diger-biyostimulan-dolgulardan-ayiran\/#1_Hafta_Fiziksel_Lifting\" >Week 1 Physical Lifting<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-12\" href=\"https:\/\/medlook.com.tr\/en\/harmonycayi-diger-biyostimulan-dolgulardan-ayiran\/#1_-_3_Ay_Fibroblast_Aktivasyonu\" >1st - 3rd Month: Fibroblast Activation<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-13\" href=\"https:\/\/medlook.com.tr\/en\/harmonycayi-diger-biyostimulan-dolgulardan-ayiran\/#3_-_9_Ay_Neokollajenezis_Yeni_Kolajen_Uretimi\" >3rd - 9th Month: Neocollagenesis (New Collagen Production)<\/a><\/li><\/ul><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-14\" href=\"https:\/\/medlook.com.tr\/en\/harmonycayi-diger-biyostimulan-dolgulardan-ayiran\/#Bolum_4_Hangi_Bolgelere_Uygulanir_%22Lateral_Lifting%22_Kavrami\" >Section 4: Which Areas Is It Applied? The Concept of \"Lateral Lifting\"<\/a><ul class='ez-toc-list-level-3' ><li class='ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-15\" href=\"https:\/\/medlook.com.tr\/en\/harmonycayi-diger-biyostimulan-dolgulardan-ayiran\/#Ideal_Uygulama_Alanlari_C-Shape\" >Ideal Application Areas (C-Shape)<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-16\" href=\"https:\/\/medlook.com.tr\/en\/harmonycayi-diger-biyostimulan-dolgulardan-ayiran\/#Uygulanmayan_Bolgeler\" >Not Applicable Regions<\/a><\/li><\/ul><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-17\" href=\"https:\/\/medlook.com.tr\/en\/harmonycayi-diger-biyostimulan-dolgulardan-ayiran\/#Bolum_5_Uygulama_Sureci_Medlook_Standartlari\" >Section 5: Implementation Process: Medlook Standards<\/a><ul class='ez-toc-list-level-3' ><li class='ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-18\" href=\"https:\/\/medlook.com.tr\/en\/harmonycayi-diger-biyostimulan-dolgulardan-ayiran\/#Adim_Adim_Surec\" >Step by Step Process<\/a><\/li><\/ul><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-19\" href=\"https:\/\/medlook.com.tr\/en\/harmonycayi-diger-biyostimulan-dolgulardan-ayiran\/#Bolum_6_HArmonyCa_Kimler_Icin_Uygundur\" >Section 6: Who is HArmonyCa Suitable for?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-20\" href=\"https:\/\/medlook.com.tr\/en\/harmonycayi-diger-biyostimulan-dolgulardan-ayiran\/#Bolum_7_Medlook_Poliklinigi_Istanbul_Nisantasi_Farki\" >Section 7: Medlook Polyclinic Istanbul Ni\u015fanta\u015f\u0131 Difference<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-21\" href=\"https:\/\/medlook.com.tr\/en\/harmonycayi-diger-biyostimulan-dolgulardan-ayiran\/#Sikca_Sorulan_Sorular_SSS\" >Frequently Asked Questions (FAQ)<\/a><ul class='ez-toc-list-level-3' ><li class='ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-22\" href=\"https:\/\/medlook.com.tr\/en\/harmonycayi-diger-biyostimulan-dolgulardan-ayiran\/#Kaliciligi_ne_kadardir\" >How long does it last?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-23\" href=\"https:\/\/medlook.com.tr\/en\/harmonycayi-diger-biyostimulan-dolgulardan-ayiran\/#Eritilebilir_mi\" >Can it be melted?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-24\" href=\"https:\/\/medlook.com.tr\/en\/harmonycayi-diger-biyostimulan-dolgulardan-ayiran\/#Islem_cok_agrili_midir\" >Is the procedure very painful?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-25\" href=\"https:\/\/medlook.com.tr\/en\/harmonycayi-diger-biyostimulan-dolgulardan-ayiran\/#Hemen_isime_donebilir_miyim\" >Can I go back to work right away?<\/a><\/li><\/ul><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-26\" href=\"https:\/\/medlook.com.tr\/en\/harmonycayi-diger-biyostimulan-dolgulardan-ayiran\/#Gelecegin_Teknolojisiyle_Bugunden_Tanisin\" >Meet the Technology of the Future Today<\/a><\/li><\/ul><\/nav><\/div>\n<h2><span class=\"ez-toc-section\" id=\"Bolum_1_Hibrit_Teknoloji_Nedir_11_Nasil_3_Eder\"><\/span>Part 1: What is Hybrid Technology? How Does 1+1 Make 3?<span class=\"ez-toc-section-end\"><\/span><\/h2><p>To understand all the other products, it is first necessary to grasp what HArmonyCa is at a molecular level. Most products on the market have a \u201csingular\u201d effect. HArmonyCa is not a cocktail; it is a matrix that is molecularly combined at the production stage.<\/p><h3><span class=\"ez-toc-section\" id=\"Icerigin_Anatomisi\"><\/span>Anatomy of Content<span class=\"ez-toc-section-end\"><\/span><\/h3><ul><li><strong>%70 \u00c7apraz Ba\u011fl\u0131 Hyaluronik Asit (HA):<\/strong> This is the carrier and volumizing part of the product. As soon as it is injected, it lifts the tissue (Lifting), moisturizes and provides instant satisfaction.<\/li><li><strong>%30 Kalsiyum Hidroksiapatit (CaHA) Mikrok\u00fcreleri:<\/strong> These are microscopic particles, 25-45 microns in diameter, homogeneously distributed inside the HA gel. These particles act as a \u201cbiological scaffold\u201d for the body to produce its own collagen.<\/li><\/ul><p>In HArmonyCa, these two components complement each other, not compete with each other. HA keeps CaHA spheres in the target area by preventing them from scattering, while CaHA weaves the new collagen network that will take its place as HA dissolves.<\/p><h2>Part 2: 5 Key Differences that Set HArmonyCa Apart<\/h2><p>The aesthetic world already had powerful biostimulants such as Sculptra (PLLA), Radiesse (CaHA), Ellanse (PCL). So why is HArmonyCa in a different category?<\/p><h3>1. The \u201cInstant Gratification\u201d Difference<\/h3><p>The biggest disadvantage of other biostimulants (e.g. Sculptra) is the need to wait 4-6 weeks to see the result. When the patient leaves the clinic, there is only edema (swelling) on the face and when this swelling goes down, it returns to its original state; the effect starts months later.<br \/><strong>The HArmonyCa Difference:<\/strong> \u0130\u00e7indeki %70 oran\u0131ndaki \u00e7apraz ba\u011fl\u0131 Hyaluronik Asit sayesinde, hasta koltuktan kalkt\u0131\u011f\u0131 anda y\u00fcz\u00fcndeki de\u011fi\u015fimi, lifting etkisini ve \u00e7ene hatt\u0131ndaki keskinle\u015fmeyi g\u00f6r\u00fcr. &#8220;Bekleme s\u00fcresi&#8221; yoktur.<\/p><h3><span class=\"ez-toc-section\" id=\"2_Kullanima_Hazir_Formulasyon_No_Preparation\"><\/span>2. Ready to Use Formulation (No Preparation)<span class=\"ez-toc-section-end\"><\/span><\/h3><p>PLLA-based products (Sculptra, Lanluma) need to be mixed with sterile water, shaken and hydrated hours or even days before application. There is a risk of clumping in this process.<br \/><strong>The HArmonyCa Difference:<\/strong> The product comes in a pre-filled syringe, ready to use. No risk of mixing error. Homogeneous distribution is guaranteed.<\/p><h3><span class=\"ez-toc-section\" id=\"3_Masaj_Gerektirmemesi_Post-Op_Konfor\"><\/span>3. No Massage Required (Post-Op Comfort)<span class=\"ez-toc-section-end\"><\/span><\/h3><p>For some biostimulants, it is mandatory for the patient to massage for 5 minutes, 5 times a day, 5 times a day for 5 days after the procedure (5-5-5 rule) to prevent the formation of nodules (lumps).<br \/><strong>The HArmonyCa Difference:<\/strong> The hyaluronic acid gel envelops the CaHA particles like a cushion. This physically prevents the particles from clumping together. The patient does not need to massage at home.<\/p><h3><span class=\"ez-toc-section\" id=\"4_Kompozit_Matriks_Yapisi\"><\/span>4. Composite Matrix Structure<span class=\"ez-toc-section-end\"><\/span><\/h3><p>In other CaHA-based products such as Radiesse, the carrier is usually \u201cCMC\u201d (Carboxymethyl Cellulose) gel. This gel is absorbed by the body very quickly (in 1-2 months). In this process, the filler may lose volume.<br \/><strong>The HArmonyCa Difference:<\/strong> The substance used as a carrier is long-lasting and cross-linked Hyaluronic Acid. This prolongs the product's residence time in the tissue and prevents volume loss during the biostimulation process.<\/p><h3><span class=\"ez-toc-section\" id=\"5_Yan_Etki_Profilinin_Dusuklugu\"><\/span>5. Low Side Effect Profile<span class=\"ez-toc-section-end\"><\/span><\/h3><p>HArmonyCa is painless during application thanks to its lidocaine (local anesthetic). In addition, its hybrid structure minimizes the risk of edema and inflammation compared to pure biostimulants.<\/p><p>For scientific studies examining the effects of hybrid fillers on tissue integration and collagen synthesis <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/34783162\/\" target=\"_blank\" rel=\"noopener sponsored\"><strong>Clinical trials in the PubMed database<\/strong><\/a> you can examine.<br \/><img decoding=\"async\" src=\"https:\/\/medlook.com.tr\/wp-content\/uploads\/2026\/01\/2-14.webp\" alt=\"\" title=\"\"><\/p><h2><span class=\"ez-toc-section\" id=\"Bolum_3_Etki_Mekanizmasi_Cildin_Altinda_Neler_Oluyor\"><\/span>Section 3: Mechanism of Action: What Happens Under the Skin?<span class=\"ez-toc-section-end\"><\/span><\/h2><p>When HArmonyCa is injected, the biological process works like a symphony:<\/p><h3><span class=\"ez-toc-section\" id=\"1_Hafta_Fiziksel_Lifting\"><\/span>Week 1 Physical Lifting<span class=\"ez-toc-section-end\"><\/span><\/h3><p>Hyaluronic acid molecules are located in the deep layers of the skin (sub-dermis). By retaining water, it stretches the skin and creates a lifting effect. The tired expression on the face is erased.<\/p><h3>1st - 3rd Month: Fibroblast Activation<\/h3><p>As HA is gradually integrated into the body, Calcium Hydroxyapatite (CaHA) microspheres are released. These spheres physically contact the \u201cFibroblast\u201d cells, the youth workers of the skin. This contact gives the following signal to the cells: <em>\u201cThere's a scaffolding here, surround it!\u201d<\/em><\/p><h3>3rd - 9th Month: Neocollagenesis (New Collagen Production)<\/h3><p>Fibroblasts begin to surround the CaHA spheres with new, fresh and flexible Type 1 and Type 3 collagen fibers. Elastin synthesis is also triggered. Even if HA dissolves in this process, there is no loss of volume as it is replaced by natural tissue produced by the body itself. The skin tightens, improves in quality and glows.<\/p><h2>Section 4: Which Areas Is It Applied? The Concept of \u201cLateral Lifting\u201d<\/h2><p>HArmonyCa is not a random filler in every area. In Medlook Polyclinic protocols, we use this product for a specific purpose: <strong>Stretching the Side Sides of the Face (Lateral Face).<\/strong><\/p><h3><span class=\"ez-toc-section\" id=\"Ideal_Uygulama_Alanlari_C-Shape\"><\/span>Ideal Application Areas (C-Shape)<span class=\"ez-toc-section-end\"><\/span><\/h3><ul><li><strong>Under the cheekbone:<\/strong> To stretch the hollows in the cheeks (submalar hollow) without filling them.<\/li><li><strong>Jawline Corner:<\/strong> To sharpen the jawline and lift the sagging (jowl).<\/li><li><strong>Anterior Ear Area:<\/strong> It is the most strategic point for pulling the face backwards (vector lifting).<\/li><\/ul><h3><span class=\"ez-toc-section\" id=\"Uygulanmayan_Bolgeler\"><\/span>Not Applicable Regions<span class=\"ez-toc-section-end\"><\/span><\/h3><p>HArmonyCa; lips, under the eyes (tear trough) and nose <strong>NEVER<\/strong> is not applied. These areas are very mobile and the skin is thin; biostimulants may cause nodules in these areas.<\/p><h2><span class=\"ez-toc-section\" id=\"Bolum_5_Uygulama_Sureci_Medlook_Standartlari\"><\/span>Section 5: Implementation Process: Medlook Standards<span class=\"ez-toc-section-end\"><\/span><\/h2><p>This product should only be administered with blunt, long and flexible needles called \u201cCannula\u201d. Applications with needles increase the risk of the product escaping into the vein and disrupt homogeneous distribution.<\/p><h3><span class=\"ez-toc-section\" id=\"Adim_Adim_Surec\"><\/span>Step by Step Process<span class=\"ez-toc-section-end\"><\/span><\/h3><ol><li><strong>Anesthesia<\/strong> A small amount of local anesthesia is applied to the entry points (usually 1-2 points on each side).<\/li><li><strong>Cannula Inlet<\/strong> The cannula is inserted under the skin. The product is spread not on the surface of the skin, but in the deep dermis or subcutaneous layer, using a \u201cfan\u201d or \u201ccombing\u201d technique.<\/li><li><strong>Duration:<\/strong> The whole process takes about 20-30 minutes.<\/li><li><strong>Conclusion:<\/strong> When the patient looks in the mirror, he sees the lifting effect instantly.<\/li><\/ol><h2><span class=\"ez-toc-section\" id=\"Bolum_6_HArmonyCa_Kimler_Icin_Uygundur\"><\/span>Section 6: Who is HArmonyCa Suitable for?<span class=\"ez-toc-section-end\"><\/span><\/h2><p>Not all patients are suitable candidates for this treatment. The ideal patient profile is as follows:<\/p><ul><li><strong>People with Skin Laxity (Looseness):<\/strong> Those who say, \u201cI wish he would always look like this\u201d when he pulls his face towards his ears with his fingers.<\/li><li><strong>Those who have a sunken face but do not want to \u201cswell\u201d:<\/strong> Those who are afraid that their face will swell \u201clike a pillow face\u201d with classical fillers and want a more natural and firmer look.<\/li><li><strong>The ones with the accordion lines:<\/strong> Patients with vertical lines on their cheeks when they laugh.<\/li><\/ul><p><img decoding=\"async\" src=\"https:\/\/medlook.com.tr\/wp-content\/uploads\/2026\/01\/3-14.webp\" alt=\"\" title=\"\"><\/p><h2><span class=\"ez-toc-section\" id=\"Bolum_7_Medlook_Poliklinigi_Istanbul_Nisantasi_Farki\"><\/span>Section 7: Medlook Polyclinic Istanbul Ni\u015fanta\u015f\u0131 Difference<span class=\"ez-toc-section-end\"><\/span><\/h2><p>HArmonyCa requires an advanced injection technique. Injecting the product into the wrong layer (too superficial or intramuscularly) can lead to complications. <strong>Istanbul Nisantasi<\/strong>\u2018located in the center of <strong>Medlook Polyclinic<\/strong> as:<\/p><ul><li><strong>Expertise<\/strong> Our physicians are specially trained and certified by Allergan Aesthetics for HArmonyCa application.<\/li><li><strong>Original Product:<\/strong> In our clinic, each product is opened next to the patient with its barcode.<\/li><li><strong>Holistic Approach:<\/strong> Not only this product, but according to the patient's needs <a href=\"https:\/\/medlook.com.tr\/en\/medical-aesthetic-anti-aging-2\/botox-applications\/\" target=\"_blank\" rel=\"noopener sponsored\"><strong>Botox<\/strong><\/a> or in combination with other energy-based devices (Focus Ultrasound, etc.) to maximize the result.<\/li><\/ul><h2><span class=\"ez-toc-section\" id=\"Sikca_Sorulan_Sorular_SSS\"><\/span>Frequently Asked Questions (FAQ)<span class=\"ez-toc-section-end\"><\/span><\/h2><h3><span class=\"ez-toc-section\" id=\"Kaliciligi_ne_kadardir\"><\/span>How long does it last?<span class=\"ez-toc-section-end\"><\/span><\/h3><p>While the effect of hyaluronic acid lasts 9-12 months, the permanence of the results thanks to the new collagen production stimulated by CaHA <strong>18-24 months<\/strong> can last up to a year. This is much longer than with conventional fillings.<\/p><h3><span class=\"ez-toc-section\" id=\"Eritilebilir_mi\"><\/span>Can it be melted?<span class=\"ez-toc-section-end\"><\/span><\/h3><p>Yes, partially. The Hyaluronic Acid component in the product can be dissolved with the enzyme Hyaluronidase. This provides a safety valve in case of a possible asymmetry or excess volume. Pure CaHA or PLLA fillers do not have this possibility.<\/p><h3><span class=\"ez-toc-section\" id=\"Islem_cok_agrili_midir\"><\/span>Is the procedure very painful?<span class=\"ez-toc-section-end\"><\/span><\/h3><p>No, it does not. The product contains lidocaine (anesthetic). The use of a cannula also minimizes pain. Patients usually only feel a slight pressure.<\/p><h3><span class=\"ez-toc-section\" id=\"Hemen_isime_donebilir_miyim\"><\/span>Can I go back to work right away?<span class=\"ez-toc-section-end\"><\/span><\/h3><p>Exactly. It's a \u201clunch break\u201d procedure. Since a cannula is used, there is very little risk of bruising. There may be a slight edema but it does not affect social life.<\/p><h2><span class=\"ez-toc-section\" id=\"Gelecegin_Teknolojisiyle_Bugunden_Tanisin\"><\/span>Meet the Technology of the Future Today<span class=\"ez-toc-section-end\"><\/span><\/h2><p>HArmonyCa is a revolutionary product that closes the era of \u201ceither volume or tightening\u201d in aesthetic medicine and starts the era of \u201cboth volume and tightening\u201d. If you want to make a biological investment in your skin, not just a temporary filling; discover the power of hybrid technology. To say goodbye to sagging, loss of elasticity and fatigue on your face in one session <strong>Medlook Polyclinic's expert physician staff in Ni\u015fanta\u015f\u0131, Istanbul<\/strong> get acquainted. Get in touch now to create your personalized treatment plan. Start the change with a free initial consultation appointment.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>","protected":false},"excerpt":{"rendered":"<p>HArmonyCA&#8217;y\u0131 Di\u011fer Biyostim\u00fclan Dolgulardan Ay\u0131ran Temel \u00d6zellikler Nelerdir? Hibrit Dolgu Devrimi Medikal estetik d\u00fcnyas\u0131, son y\u0131llarda ba\u015f d\u00f6nd\u00fcr\u00fcc\u00fc bir h\u0131zla geli\u015fiyor. Eskiden sadece &#8220;doldurma&#8221; (hacim verme) \u00fczerine kurulu olan yakla\u015f\u0131mlar, art\u0131k &#8220;yenileme&#8221; (rejenerasyon) \u00fczerine evriliyor. Hastalar\u0131m\u0131z art\u0131k sadece \u00e7\u00f6ken yanaklar\u0131n\u0131 doldurmak istemiyor; ayn\u0131 zamanda gev\u015feyen ciltlerinin s\u0131k\u0131la\u015fmas\u0131n\u0131, kalitesinin artmas\u0131n\u0131 ve zaman\u0131n etkilerine h\u00fccresel d\u00fczeyde direnmesini [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":21174,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_joinchat":[],"footnotes":""},"categories":[14],"tags":[517,269,519,515,516,72,98,518,521,77,87,522,520],"class_list":["post-21170","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-saglikli-yasam","tag-akilli-dolgu","tag-ameliyatsiz-estetik","tag-biyostimulan","tag-harmonyca","tag-hibrit-dolgu","tag-hyaluronik-asit","tag-istanbul","tag-kalsiyum-hidroksiapatit","tag-kolajen-asisi","tag-medlook","tag-nisantasi","tag-sculptra-farki","tag-yuz-germe"],"_links":{"self":[{"href":"https:\/\/medlook.com.tr\/en\/wp-json\/wp\/v2\/posts\/21170","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medlook.com.tr\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/medlook.com.tr\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/medlook.com.tr\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/medlook.com.tr\/en\/wp-json\/wp\/v2\/comments?post=21170"}],"version-history":[{"count":0,"href":"https:\/\/medlook.com.tr\/en\/wp-json\/wp\/v2\/posts\/21170\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/medlook.com.tr\/en\/wp-json\/wp\/v2\/media\/21174"}],"wp:attachment":[{"href":"https:\/\/medlook.com.tr\/en\/wp-json\/wp\/v2\/media?parent=21170"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/medlook.com.tr\/en\/wp-json\/wp\/v2\/categories?post=21170"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/medlook.com.tr\/en\/wp-json\/wp\/v2\/tags?post=21170"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}